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Antigenic Specificity | CBX3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect CBX3 in human, mouse and rat samples. Background: Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members (alpha, beta, and gamma) are primarily associated with centromeric heterochromatin? However, HP1beta and gamma also localize to euchromatic sites in the genome. HP1 proteins are approximately 25 kDa in size and contain a conserved amino terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain. The chromodomain facilitates binding to histone H3 tri-methylated at Lys9, a histone mark closely associated with centromeric heterochroma |
Immunogen | Immunogen: Fusion protein of human CBX3. Positive Control: Western Blot: Various cell lysates |
Other Names | [HECH; HP1-GAMMA; HP1Hs-gamma; HP1gamma], [CBX3; CBX3; HECH; HP1-GAMMA; HP1Hs-gamma; HP1 gamma] |
Gene, Accession # | [CBX3], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185 |
Catalog # | MBS841061 |
Price | $385 |
Order / More Info | CBX3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |