CBX5 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CBX5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total CBX5 protein. Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.Saunders W.S., J. Cell Sci. 104:573-582(1993).Ye Q., J. Biol. Chem. 271:14653-14656(1996).Minc E., Chromosoma 108:220-234(1999). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CBX5. |
| Other Names | [HP1 alpha; HP1A; antigen p25; chromobox protein homolog 5; heterochromatin protein 1 alpha] |
| Gene, Accession # | [CBX5], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973 |
| Catalog # | MBS9406640 |
| Price | $200, $255 |
| Order / More Info | CBX5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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