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Antigenic Specificity | UBA7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.9mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total UBA7 protein. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. |
Immunogen | Immunogen: Fusion protein of human UBA7 Immunogen Type: Protein |
Other Names | [D8; UBE2; UBA1B; UBE1L] |
Gene, Accession # | [UBA7], Gene ID: 7318, NCBI: NP_003326.2, UniProt: P41226 |
Catalog # | MBS9417029 |
Price | $255 |
Order / More Info | UBA7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |