SEK1 / MKK4 / JKK1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SEK1 / MKK4 / JKK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, dog |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Affinity purified polyclonal antibody to detect SEK1 (MKK4/JKK1) in human, mouse and dog samples. Background: SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflammatory cytokines. Activation of SEK1 occurs thromugh phosphorylation of serine and threonine residues at positions 257 and 261, respectively, by MEKK. Like MEK, SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop. Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses the stress-activated signal transduction. |
| Immunogen | Immunogen: Synthetic peptide surrounding amino acid 347 of mouse SEK1. Positive Control: Western Blot: Jurkat cell lysate |
| Other Names | n/a |
| Gene, Accession # | [SEK1/MKK4/JKK1] |
| Catalog # | MBS840407 |
| Price | $150, $290 |
| Order / More Info | SEK1 / MKK4 / JKK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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