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Antigenic Specificity | Human Zinc finger protein RFP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'-linked polyubiquitin chains; the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-strand |
Immunogen | Immunogen: Recombinant human Zinc finger protein RFP protein(214-513aa) Species: Human Research Area: Epigenetics and Nuclear Signaling Target Names: TRIM27 |
Other Names | [Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (RING-type E3 ubiquitin transferase TRIM27) (Ret finger protein) (Tripartite motif-containing protein 27), TRIM27, RFP RNF76], [TRIM27; TRIM27; RFP; RNF76; RFP; RNF76] |
Gene, Accession # | [TRIM27], Gene ID: 5987, NCBI: NP_006501.1, UniProt: P14373 |
Catalog # | MBS1492534 |
Price | $120, $160 |
Order / More Info | Human Zinc finger protein RFP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |