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Antigenic Specificity | Human TRAIL/Apo2L |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein A purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. |
Immunogen | n/a |
Other Names | [human TRAILApo2], [TNFSF10; TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L; APO2L; TRAIL; Apo-2L] |
Gene, Accession # | [TRAIL/Apo2L], Gene ID: 8743, NCBI: NP_001177871.1, UniProt: P50591 |
Catalog # | MBS690389 |
Price | $440 |
Order / More Info | Human TRAIL/Apo2L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |