GSK3B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGSK3B
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman, rat, mouse, monkey
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionGlycogen synthase kinase 3 (GSK-3), a serine-threonine kinase with two isoforms (alpha and beta), was originally discovered as a key enzyme in glycogen metabolism. GSK-3 was subsequently shown to function in cell division, proliferation, motility and survival. GSK-3 plays a role in a number of pathological conditions including cancer and diabetes and is increasingly seen as an important component of neurological diseases. GSK-3 phosphorylates tau and presenilin-1, which are involved in the development of Alzheimer's disease. Both isoforms of GSK-3 are ubiquitously expressed, although particularly high levels of GSK-3beta are found in the brain where it is involved in synaptic plasticity, possibly via regulation of NMDA receptor trafficking.
ImmunogenImmunogen: Purified recombinant fragment of human GSK3B expressed in E. Coli.
Other Names[GSK-3beta; GSK3-beta], [GSK3B; GSK3B; GSK-3 beta]
Gene, Accession #[GSK3B], Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841
Catalog #MBS850776
Price$280
Order / More InfoGSK3B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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