FOXP3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FOXP3 |
| Clone | [3G3] |
| Host Species | Mouse |
| Reactive Species | human, monkey, mouse. |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistology (IH) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion (amino acids 2-136) of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited di |
| Immunogen | Immunogen: Full-length His-tagged mouse FOXP3 protein Quantity and Buffer: 0.5 ml at 200ug/ml with BSA and azide |
| Other Names | [JM2; AIID; DIETER; IPEX; MGC141961; MGC141963; PIDX; XPID; FOXP3delta7; forkhead box protein P3; immune dysregulation; polyendocrinopathy; enteropathy; X-linked; immunodeficiency; polyendocrinopathy; enteropathy; X-linked; scurfin], [FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; IPEX] |
| Gene, Accession # | [FOXP3], Gene ID: 50943, NCBI: NP_001107849.1, UniProt: Q9BZS1 |
| Catalog # | MBS438434 |
| Price | $190, $340, $340 |
| Order / More Info | FOXP3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, Ocheltree EL, Greenberg PD, Ochs HD, Rudensky AY: Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A. 2006;103(17):6659-64.2. Law JP, Hirschkorn DF, Owen RE, Biswas HH, Norris PJ, Lanteri MC: The importance of Foxp3 antibody and fixation/permeabilization buffer combinations in identifying CD4 CD25 Foxp3 regulatory T cells. Cytometry A. 2009;75(12):1040-50. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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