TNIP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNIP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mousepredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: TNIP1 Antibody detects endogenous levels of TNIP1. Description: Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this f
ImmunogenImmunogen: A synthesized peptide derived from human TNIP1. Tissue Specificity: Ubiquitous. Strongly expressed in peripheral blood lymphocytes, spleen and skeletal muscle, and is weakly expressed in the brain. In peripheral blood mononucleocytes, isoform 4 is mainly expressed and isoform 1 and isoform 7 are almost not expressed. Expression of isoform 1 and isoform 7 increases in leukemic cells.
Other Names[ABIN 1; HIV-1 Nef-interacting protein; hVAN; KIAA0113; Naf1; Nef-associated factor 1; Nip40-1; TNFAIP3 interacting protein 1; TNFAIP3-interacting protein 1; TNIP-1; Tnip1; TNIP1_HUMAN; VAN; Virion-associated nuclear shuttling protein]
Gene, Accession #[TNIP1], Gene ID: 10318, NCBI: Q15025.2, UniProt: Q15025
Catalog #MBS9611529
Price$240, $280
Order / More InfoTNIP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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