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Antigenic Specificity | GAD-65/67 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GAD-65/67 Polyclonal Antibody detects endogenous levels of GAD-65/67 protein. GAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. Glutamate decarboxylase 1 is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominan |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human GAD-65/67 at AA range: 520-600 |
Other Names | [Rabbit GAD-65/67; GAD1; GAD; GAD67; Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform; GAD2; GAD65; Glutamate decarboxylase 2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65] |
Gene, Accession # | [GAD-65/67], Gene ID: 2571, NCBI: NP_000808.2, UniProt: Q99259 |
Catalog # | MBS9702095 |
Price | $130, $220, $325 |
Order / More Info | GAD-65/67 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |