LIN28 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LIN28 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: LIN28 antibody detects endogenous levels of total LIN28. Description: LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.Function: RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translati |
| Immunogen | Immunogen: Purified recombinant fragment of human LIN28 expressed in E. Coli Subcellular Location: Cytoplasm. Nucleus > Nucleolus. Nucleolar localization observed in 10-15% of the nuclei in differentiated myotubes (By similarity). Shuttles between the cytoplasm and the nucleus. Localizes to cytoplasmic processing bodies and stress granules. Tissue Specificity: Expressed in embryonic stem cells, placenta and testis. Tends to be up-regulated in HER2-overexpressing breast tumors. |
| Other Names | [CSDD1; FLJ12457; LIN 28; Lin 28 homolog A (C. elegans); Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; zinc finger CCHC domain containing 1; Zinc finger CCHC domain-containing protein 1] |
| Gene, Accession # | [LIN28], Gene ID: 79727, NCBI: NP_078950.1, UniProt: Q9H9Z2 |
| Catalog # | MBS9602788 |
| Price | $235, $295, $370 |
| Order / More Info | LIN28 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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