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Antigenic Specificity | KCTD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KCTD5 Antibody detects endogenous levels of KCTD5. Description: Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.Subunit Structure: Homopentamer. Interacts (via C-terminus) with GRASP55/GORASP2. Interacts with CUL3 and with ubiquitinated proteins. Interacts with adeno-associated virus 2 (AAV-2) REP proteins.Similarity: The BTB (POZ) domain is atypical and mediates the formation of a homopentamer instead of a homotetramer. Homopentamerization is due to the presence of 4 residues in the BTB (POZ) domain: Leu-56, Gly-100, Val-112 and Ala-118. |
Immunogen | Immunogen: A synthesized peptide derived from human KCTD5. Tissue Specificity: Up-regulated in peripheral blood lymphocytes stimulated through the T-cell receptor. |
Other Names | [BTB/POZ domain-containing protein KCTD5; FLJ20040; KCTD5; KCTD5_HUMAN; Potassium channel tetramerisation domain containing 5] |
Gene, Accession # | [KCTD5], Gene ID: 54442, NCBI: NP_061865.1, UniProt: Q9NXV2 |
Catalog # | MBS9611855 |
Price | $240, $280 |
Order / More Info | KCTD5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |