pTEN Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | pTEN |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes IRAK-4 (pT345) with a phosphorylated site at Threonine 345. It does not cross-react with non-phosphospecific peptide. Thephosphatase and tensin homologue (PTEN) tumor suppressoris a phosphatidylionositol D3-phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. PTEN is mutated in a wide range of cancers.In vitro, the recombinant PTEN can be regulated by phosphorylation on multiple serine and threonine residues in its C-terminus, such as CK2, GSK3beta at Ser-362, 370 and 385. It antagonizes signal transduction downstream of PI-3 kinases affecting cell proliferation, apoptosis and migration. Loss-of-function mutations in the PTEN gene lead |
| Immunogen | n/a |
| Other Names | [Phosphatase and tensin homolog; PTEN; MMAC1], [PTEN; PTEN; BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del; PTENbeta; MMAC1; TEP1] |
| Gene, Accession # | [pTEN], Gene ID: 5728, NCBI: AAD13528.1 |
| Catalog # | MBS460436 |
| Price | $285 |
| Order / More Info | pTEN Antibody from MYBIOSOURCE INC. |
| Product Specific References | Anna Maria Al-Khouri, et al (2005) Cooperative Phosphorylation of the Tumor Suppressor Phosphatase and Tensin Homologue (PTEN) by Casein Kinases and Glycogen Synthase Kinase 3b J. Biol. Chem., Vol. 280, Issue 42, 35195-35202, October 21, 2005 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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