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Antigenic Specificity | Bid |
Clone | [3C5-E5-C3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2.The encoded protein is a member of the BCL-2 family of cell death regulators.It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.[provided by RefSeq, Jul 2008]. UniPort Summary Function: The major proteolytic product p15 BID allows the release of cytochrome c By similarity.Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis.Isof |
Immunogen | Immunogen: Purified recombinant fragment of human Bid expressed in E Coli. Sensitivity: This antibody detects endogenous levels of Bid and does not cross-react with related proteins. |
Other Names | [Apoptic death agonist; Apoptotic death agonist; Apoptotic death agonist BID; BH3 interacting domain death agonist; BH3 interacting domain death agonist; BH3 interacting domain death agonist p11; BH3 interacting domain death agonist p13; BH3 interacting domain death agonist p15; BH3-interacting domain death agonist p11; BID; BID isoform ES (1b); BID isoform L (2); BID isoform Si6; BID_HUMAN; Desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; p11 BID; p13 BID; p15 BID; p22 BID], [FP497.] |
Gene, Accession # | [Bid], Gene ID: 637, NCBI: NP_001187.1, UniProt: P55957 |
Catalog # | MBS475603 |
Price | $335 |
Order / More Info | Bid Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |