Syntaxin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySyntaxin
Clone[SP-6]
Host SpeciesMouse
Reactive Speciesmouse, rat
IsotypeIgG1
FormatProtein G purified
Size0.025 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionDetects ~38kDa. Syntax ins are a family of membrane integrated Q-SNARE proteins participating in exocytosis (1). They possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. This SNARE domain binds to synaptobrevin and SNAP-25 to form the SNARE complex (2, 3). Support of syntaxin's involvement in vesicular transport and neurotransmission includes the requirement of its yeast homologs, SSO 1 and 2, in targeting and fusion of Golgi-derived vesicles with the plasma membrane (4). Syntaxin also provides the target pf clostridial neurotoxin C1, which blocks neurotransmitter release (5). The formation of 20S complex involves the interaction of VAMP with syntaxin through an ATP-dependent reaction modul
ImmunogenImmunogen: Raised against synaptic vesicle-containing fractions of immunoprecipitated human brain homogenate Immunogen Species: Human
Other Names[Mouse Human Syntaxin IgG1; Syntaxin, Clone SP-6; HPC1; P35 1; STX1; STX1A; STX1B; STX2; STX3]
Gene, Accession #Gene ID: 6804, NCBI: NP_001159375.1, UniProt: Q16623
Catalog #MBS8001934
Price$215
Order / More InfoSyntaxin Antibody from MYBIOSOURCE INC.
Product Specific References1. Bennett M.K., et al. (1993) Cell. 74(5): 863-873. 2. Walter A.M., Wiederhold K., Bruns D., Fasshaurer D. and Sorensen J.B. (2010) J Cell BIol. 188(3): 401-413. 3. Honma S., Taki K., Lei S., and Wakisaka S. (2010) Anat Rec. Epub. 4. Aalto M.K., Ronne H. and Keranen S. (1993) EMBO J. 12: 4095-4104. 5. Blasi J., et al. (1993) EMBO J. 12: 4821-4828. 6. Sollner T., et al. (1993) Cell. 75: 409-418.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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