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Antigenic Specificity | DENND4A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DENND4A antibody detects endogenous levels of total DENND4A. Function: Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter. |
Immunogen | Immunogen: A synthesized peptide derived from human DENND4A Subcellular Location: Nucleus. Tissue Specificity: Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth-and cell cycle-dependent manner. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (91%), Bovine (82%), |
Other Names | [C-myc promoter-binding protein; DENN domain-containing protein 4A; DENN/MADD domain containing 4A; DENND4A; FLJ33949; IRLB; KIAA0476; MYCPBP; MYCPP_HUMAN] |
Gene, Accession # | [DENND4A], Gene ID: 10260, NCBI: NP_001138295.1, UniProt: Q7Z401 |
Catalog # | MBS9609716 |
Price | $240, $280 |
Order / More Info | DENND4A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |