Mouse Ddr2 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Ddr2 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Ddr2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 503-537 amino acids from the Central region of Mouse Ddr2. Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. |
| Immunogen | n/a |
| Other Names | [Discoidin domain-containing receptor 2; Discoidin domain receptor 2; CD167 antigen-like family member B; Neurotrophic tyrosine kinase; receptor-related 3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10; CD167b; Ddr2; Ntrkr3; Tkt; Tyro10] |
| Gene, Accession # | [Ddr2], Gene ID: 18214, NCBI: NP_072075.2, UniProt: Q62371 |
| Catalog # | MBS9207733 |
| Price | $165, $370 |
| Order / More Info | Mouse Ddr2 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Karn T.,et al.Oncogene 8:3433-3440(1993). Lai C.,et al.Oncogene 9:877-883(1994). Labrador J.P.,et al.EMBO Rep. 2:446-452(2001). Olaso E.,et al.J. Biol. Chem. 277:3606-3613(2002). Ikeda K.,et al.J. Biol. Chem. 277:19206-19212(2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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