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Antigenic Specificity | Adenosine Receptor A2A |
Clone | [5H30] |
Host Species | Mouse |
Reactive Species | dog, guinea pig, human, mouse, rabbit, rat |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.1 mg, 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human adenosine receptor A2A at ~43kD. Adenosine receptors, a class of purinergic G-protein coupled receptors with adenosine as endogenous ligands mediate several receptor subtype-specific physiological processes that include cardiac rate, smooth muscle tone, platelet aggregation, inflammation, cell growth and death, and neurotransmission. The activity of A2A adenosine receptor is mediated by G proteins which activate adenylyl cyclase. It is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine. Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB and may suggest a new strategy for using this mechanism in neurodegenerative diseases. |
Immunogen | Immunogen: 6His-tagged full-length human recombinant A2A receptor. Epitope: third intracellular loop (SQPLPGER). |
Other Names | [-Adenosine Receptor A2A], [ADORA2A; ADORA2A; RDC8; hA2aR; ADORA2; ADORA2] |
Gene, Accession # | Gene ID: 135, NCBI: NP_000666.2, UniProt: P29274 |
Catalog # | MBS609984 |
Price | $470, $780 |
Order / More Info | Adenosine Receptor A2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |