Adenosine Receptor A2A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAdenosine Receptor A2A
Clone[5H30]
Host SpeciesMouse
Reactive Speciesdog, guinea pig, human, mouse, rabbit, rat
IsotypeIgG2a
FormatProtein G purified
Size0.1 mg, 0.2 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionRecognizes human adenosine receptor A2A at ~43kD. Adenosine receptors, a class of purinergic G-protein coupled receptors with adenosine as endogenous ligands mediate several receptor subtype-specific physiological processes that include cardiac rate, smooth muscle tone, platelet aggregation, inflammation, cell growth and death, and neurotransmission. The activity of A2A adenosine receptor is mediated by G proteins which activate adenylyl cyclase. It is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine. Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB and may suggest a new strategy for using this mechanism in neurodegenerative diseases.
ImmunogenImmunogen: 6His-tagged full-length human recombinant A2A receptor. Epitope: third intracellular loop (SQPLPGER).
Other Names[-Adenosine Receptor A2A], [ADORA2A; ADORA2A; RDC8; hA2aR; ADORA2; ADORA2]
Gene, Accession #Gene ID: 135, NCBI: NP_000666.2, UniProt: P29274
Catalog #MBS609984
Price$470, $780
Order / More InfoAdenosine Receptor A2A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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