Mouse/Human CD44 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse/Human CD44
Clone[IM7]
Host SpeciesRat
Reactive Speciesmouse, human
IsotypeIgG2b
Formatunconjugated
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionCD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
Immunogenn/a
Other Names[Mouse/Human CD44; CD44 antigen; CD44; CDw44; Epican; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD44; LHR; MDU2; MDU3; MIC4]
Gene, Accession #[CD44], Gene ID: 12505, NCBI: NP_001034240.1, UniProt: P15379
Catalog #MBS2553915
Price$85, $100
Order / More InfoMouse/Human CD44 Antibody from MYBIOSOURCE INC.
Product Specific References1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Haynes BF, et al. 1991. Cancer Cells 3:347. 3. Goldstein LA, et al. 1989. Cell 56:1063. 4. Mikecz K, et al. 1995. Nat. Med. 1:558. 5. Hegde V, et al. 2008. J. Leukocyte Biol. 84:134. 6. Liu T, et al. 2009. Biol. Direct 4:40.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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