MEK1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MEK1 |
| Clone | [263P15] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes a protein of 45 kDa, identified as MEK1 (also known as ERK kinase 1, MAPK kinase 1, and MKK1). MEK1 is a member of a family of tyrosine/threonine protein kinases that activate the ERK1&2/MAPK enzymes by phosphorylating both the threonine and tyrosine residues of the threonine ? glutamic acid ? tyrosine (TEY) motif located within the activation loop. MEK1 shares approximately 80% homology with the closely related dual specificity protein kinase MEK2. Active Raf family members phosphorylate MEK1 at serines 218 and 222, thereby activating it. Serine 298 of MEK1 is phosphorylated by PAK proteins, which promotes MEK1 binding to c-Raf and its subsequent phosphorylation of MEK1, leading to activation of the MAPK pathway. T |
| Immunogen | Immunogen: Recombinant human MEK1 protein. |
| Other Names | [ERK Kinase 1; MAPK KInase 1 and MKK1], [MAP2K1; MAP2K1; CFC3; MEK1; MKK1; MAPKK1; PRKMK1; MEK1; PRKMK1; MAP kinase kinase 1; MAPKK 1; MKK1; MEK 1] |
| Gene, Accession # | [MEK1], Gene ID: 5604, NCBI: NP_002746.1, UniProt: Q02750 |
| Catalog # | MBS395325 |
| Price | $625 |
| Order / More Info | MEK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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