Edit |   |
---|---|
Antigenic Specificity | TLR8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous TLR8 protein. The protein encoded by TLR8 (toll like receptor 8) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Rabbit TLR8] |
Gene, Accession # | [TLR8], Gene ID: 51311, NCBI: NP_619542.1, UniProt: Q9NR97 |
Catalog # | MBS9707835 |
Price | $130, $220, $325 |
Order / More Info | TLR8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |