Mouse CD22 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD22
Clone[2D6 (also known as NIMR-6]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG1 kappa
Formatunconjugated
Size0.5 mg
Concentrationn/a
ApplicationsFlow Cytometry
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DescriptionSpecificity: CD22 (Mr 150 kDa), a B lymphocyte adhesion molecule. CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM^+IgD^+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. ^1, 2 CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. ^2-4 Its intr
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS673256
Price$310
Order / More InfoMouse CD22 Antibody from MYBIOSOURCE INC.
Product Specific References1. Symington, F.W., B. Subbarao, D.E. Mosier, and J. Sprent. 1982. Immunogenetics 16:381.2. Torres, R.M., C-L. Law, L. Santos-Argumedo, P.A. Kirkham, K. Grabstein, R.M.E. Parkhouse, and E.A. Clark. 1992. J. Immunol. 149:2641.3. Erickson, L.D., L.T. Tygrett, S.K. Bhatia, K.H. Grabstein, and T.J. Waldschmidt. 1996. Int. Immunol. 8:1121.4. Law C.-L. Aruffo, A. Chandran, K.A. Doty, R.T. and Clark, E.A. 1995. J. Immunol. 155:3368.5. Law, C.-L., S.P. Sidorenko, and E.A. Clark. 1994. Immunol. Today 15:442.6. Pezzutto, A., Dorken, B., Moldenhauer, G. amd Clark, E.A. 1988. J. Immunol. 140:1791.7. Doody, G.M., L.B. Justement, C.C. Delbrias, R.J. Matthews, J. Lin, M.L. Thomas, and D.T. Fearon. 1995. Science 269:242.8. Law, C.-L., S.P. Sidorenko, K.A. Chandran, Z. Zhao, S.-H. Shen, E.H. Fischer, and E.A. Clark. 1996. J. Exp. Med. 183:547.9. O'Keefe, T.L., G.T. Williams, S.L. Davies, and M.S. Neuberger. 1996. Science 274:798.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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