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Antigenic Specificity | Rnf216 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Rnf216. It was validated on Western BlotTarget Description: Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Rnf216 |
Other Names | [E3 ubiquitin-protein ligase RNF216 isoform A; E3 ubiquitin-protein ligase RNF216; E3 ubiquitin-protein ligase RNF216; ring finger protein 216; RING finger protein 216; Triad domain-containing protein 3; UbcM4-interacting protein 83; Ubiquitin-conjugating enzyme 7-interacting protein 1] |
Gene, Accession # | [RNF216], Gene ID: 108086, NCBI: NP_542128.2, UniProt: P58283 |
Catalog # | MBS3213582 |
Price | $335 |
Order / More Info | Rnf216 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |