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Antigenic Specificity | RET |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for RET detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular signalling molecules. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of org |
Immunogen | Immunogen: E Coli-derived human RET recombinant protein (Position: L29-V304). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit for IHC(P). |
Other Names | [Proto-oncogene tyrosine-protein kinase receptor Ret; ret proto-oncogene; Proto-oncogene tyrosine-protein kinase receptor Ret; Cadherin family member 12; Proto-oncogene c-Ret; RET; CDHF12; CDHR16; PTC; RET51] |
Gene, Accession # | [RET], Gene ID: 5979, NCBI: NP_065681.1, UniProt: P07949 |
Catalog # | MBS1752429 |
Price | $315 |
Order / More Info | RET Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Ceccherini I, Bocciardi R, Luo Y, et al. (1993). Exon structure and flanking intronic sequences of the human RET proto-oncogene. Biochem. Biophys. Res. Commun. 196 (3): 1288-1295. 2. Knowles PP, Murray-Rust J, Kjaer S, et al. (2006). Structure and chemical inhibition of the RET tyrosine kinase domain. J. Biol. Chem.281 (44): 33577-87. |