K+/Cl- Cotransporter (KCC2) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | K+/Cl- Cotransporter (KCC2) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot (IB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes human, mouse and rat KCC2. KCC2 is a member of the cation-chloride cotransporter gene family. KCCs lower intracellular chloride concentrations below the electrochemical equilibrium potential. Depending on the concentration gradients of potassium and chloride, KCC2 can operate as a net efflux or influx pathway. KCC2 is expressed at high levels in neurons throughout the nervous system and is localized at inhibitory synapses of the spinal cord. Studies in mice have shown that KCC2 reduces GABAs inhibitory signaling resulting in motor defects, epilepsy, and anxiety-like behavior. |
| Immunogen | Antigen: Fusion protein consisting of aa 932-1043 of rat KCC2 (accession no. NP_599190). |
| Other Names | [K+/Cl-Cotransporter (KCC2)], [kcc-1; kcc-1] |
| Gene, Accession # | [KCC2], Gene ID: 177495, NCBI: NP_001294073.1, UniProt: N1NVB5 |
| Catalog # | MBS190651 |
| Price | $410 |
| Order / More Info | K+/Cl- Cotransporter (KCC2) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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