Mouse Mavs (N-term), 1-30 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Mavs (N-term), 1-30 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.35 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs. Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity). |
| Immunogen | n/a |
| Other Names | [Mitochondrial antiviral-signaling protein; MAVS; CARD adapter inducing interferon beta; Cardif; Interferon beta promoter stimulator protein 1; IPS-1; Virus-induced-signaling adapter; VISA; Mavs; Ips1; Visa] |
| Gene, Accession # | [Mavs], Gene ID: 228607, NCBI: NP_001193314.1, UniProt: Q8VCF0 |
| Catalog # | MBS9201907 |
| Price | $165, $370 |
| Order / More Info | Mouse Mavs (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ichinohe, T., et al. Nat. Immunol. 11(5):404-410(2010) DeWitte-Orr, S.J., et al. PLoS Pathog. 6 (3), E1000829 (2010) : Suthar, M.S., et al. PLoS Pathog. 6 (2), E1000757 (2010) : Dong, X., et al. PLoS Pathog. 6 (7), E1001001 (2010) : Faul, E.J., et al. PLoS Pathog. 6 (7), E1001016 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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