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Antigenic Specificity | RBBP8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 3 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total RBBP8 protein. The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human retinoblastoma binding protein 8 |
Other Names | [RIM; COM1; CTIP; JWDS; SAE2; SCKL2] |
Gene, Accession # | [RBBP8], Gene ID: 5932, NCBI: NP_002885.1, UniProt: Q99708 |
Catalog # | MBS9410103 |
Price | $255 |
Order / More Info | RBBP8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |