SETDB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySETDB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionPolyclonal antibody to detect SETDB1 in human and mouse samples. Background: The Erg-associated protein with SET domain (ESET), also known as SET domain, bifurcated 1 (SETDB1) protein, is a member of a family of histone lysine methyltransferases, each of which contains a conserved catalytic SET domain originally identified in Drosophila, Enhancer of zeste, and Trithorax proteins. ESET also contains tudor and methyl-CpG-binding domains, which may coordinate binding to methylated histones and methylated DNA, respectively. ESET methylates histone H3 Lys9, creating a transcriptionally repressive mark that facilitates gene silencing. However, unlike SUV39H histone H3 Lys9 methyltransferases, which function mainly in heterochromatin regions such
ImmunogenImmunogen: Fusion protein of human SETDB1. Positive Control: Western Blot: Various cell lysates
Other Names[ESET; H3-K9-HMTase4; KG1T, KIAA0067; KMT1E.], [SETDB1; SETDB1; ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4; KIAA0067; KMT1E; ESET; H3-K9-HMTase 4]
Gene, Accession #[SETDB1], Gene ID: 9869, NCBI: NP_001138887.1, UniProt: Q15047
Catalog #MBS840596
Price$385
Order / More InfoSETDB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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