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Antigenic Specificity | Myc |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Myc (Phospho-Ser62) Antibody detects endogenous levels of Myc only when phosphorylated at serine 62. This gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthes |
Immunogen | Immunogen: The antibody was produced against synthesized phosphopeptide derived from human Myc around the phosphorylation site of serine 62(P-L-SP-P-S). |
Other Names | n/a |
Gene, Accession # | [Myc], NCBI: NP_955602.1 |
Catalog # | MBS417181 |
Price | $325 |
Order / More Info | Myc Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |