Edit |   |
Antigenic Specificity | Phospho-VEGFR2 (Tyr951) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-VEGFR2 (Tyr951) antibody detects endogenous levels of VEGFR2 only when phosphorylated at Tyrosine 951. Description: VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2.Function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoske |
Immunogen | Immunogen: A synthesized peptide derived from human VEGFR2 around the phosphorylation site of Tyrosine 951 Subcellular Location: Membrane. Tissue Specificity: Detected in cornea (at protein level). Widely expressed. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (82%), Bovine (82%), Sheep (82%), Rabbit (82%), Dog (82%) |
Other Names | [CD309; CD309 antigen; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; FLK1; FLK1, mouse, homolog of; Kdr; Kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; Tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; VEGFR 2; VEGFR; VEGFR-2; VEGFR2; VGFR2_HUMAN] |
Gene, Accession # | [VEGFR2], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS9601052 |
Price | $240, $280 |
Order / More Info | Phospho-VEGFR2 (Tyr951) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |