Edit |   |
---|---|
Antigenic Specificity | CRTC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 3.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CRTC3 (NP 073606.3). Immunogen Sequence: MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHGGSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRPRSCDVGGGNAFPHNGQNLG |
Other Names | [CRTC3; TORC-3; TORC3; CREB-regulated transcription coactivator 3] |
Gene, Accession # | [CRTC3], Gene ID: 64784, NCBI: NP_001036039.1, UniProt: Q6UUV7 |
Catalog # | MBS9140589 |
Price | $260 |
Order / More Info | CRTC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |