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Antigenic Specificity | Memo1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Memo1. It was validated on Western BlotTarget Description: Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Memo1 is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. |
Immunogen | n/a |
Other Names | [protein MEMO1; Protein MEMO1; protein MEMO1; mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; Memo-1] |
Gene, Accession # | [MEMO1], Gene ID: 298787, NCBI: NP_001025088, UniProt: Q4QQR9 |
Catalog # | MBS3213000 |
Price | $335 |
Order / More Info | Memo1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |