ERBB2 (C-term T1172/S1174), 1151-1179 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityERBB2 (C-term T1172/S1174), 1151-1179
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.4
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis ERBB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1179 amino acids from the C-terminal region of human ERBB2. This gene encodes a member of the epidermal growth factor(EGF) receptor family of receptor tyrosine kinases. This proteinhas no ligand binding domain of its own and therefore cannot bindgrowth factors. However, it does bind tightly to other ligand-boundEGF receptor family members to form a heterodimer, stabilizingligand binding and enhancing kinase-mediated activation ofdownstream signalling pathways, such as those involvingmitogen-activated protein kinase and phosphatidylinositol-3 kinase.Allelic variations at amino acid positions 654 and 655
Immunogenn/a
Other Names[Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340; ERBB2; HER2; MLN19; NEU; NGL]
Gene, Accession #[ERBB2], Gene ID: 2064, NCBI: NP_001005862.1, UniProt: P04626
Catalog #MBS9206502
Price$165, $370
Order / More InfoERBB2 (C-term T1172/S1174), 1151-1179 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGeradts, J., et al. Cancer Invest. 28(9):969-977(2010) Zaoui, K., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18517-18522(2010) Oliveras, G., et al. Ann. N. Y. Acad. Sci. 1210, 86-92 (2010) : Han, J.S., et al. Anticancer Res. 30(9):3407-3412(2010) Stackievicz, R., et al. Isr. Med. Assoc. J. 12(5):290-295(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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