Human PIN1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human PIN1 |
| Clone | [P3G8AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 k |
| Format | unconjugated |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA, PLK I, Wee, and Myt1 kinases), several transcription factors like beta-Catenin, c-Jun, and the tumor suppressor protein p53, and some specific proteins like the RN |
| Immunogen | Immunogen: Anti-human PIN1 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PIN1 amino acids 1-163 purified from E Coli. |
| Other Names | [PIN1; PIN1, Mouse Human; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; EC 5.2.1.8; Rotamase Pin1; PPIase Pin1; DOD; UBL5; PIN1; PPIase], [PIN1; PIN1; DOD; UBL5; PPIase Pin1] |
| Gene, Accession # | [PIN1], Gene ID: 5300, NCBI: NP_006212.1 |
| Catalog # | MBS140199 |
| Price | $140, $205, $505 |
| Order / More Info | Human PIN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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