FEN1 - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FEN1 - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FEN1 |
| Other Names | [flap endonuclease 1; Flap endonuclease 1; flap endonuclease 1; flap structure-specific endonuclease 1; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1] |
| Gene, Accession # | [FEN1], Gene ID: 2237, NCBI: NP_004102.1, UniProt: P39748 |
| Catalog # | MBS3222340 |
| Price | $335 |
| Order / More Info | FEN1 - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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