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Antigenic Specificity | Setd1a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect Setd1a in mouse samples. Background: SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression. |
Immunogen | Immunogen: Polyclonal antibody raised in rabbit against mouse Setd1a (Set domain containing 1A), using three KLH-conjugated synthetic peptides: two containing an amino acid sequence from the N-terminal part of the protein and one containing an amino acid sequence from the central part of the protein. Positive Control: Western blot: NIH3T3 and embryonic stem cells, ELISA: Peptides. |
Other Names | [SET1; SET1A; KMT2F], [SETD1A; SETD1A; Set1; KMT2F; Set1A;; hSET1A] |
Gene, Accession # | [Setd1a], Gene ID: 9739, NCBI: NP_055527.1, UniProt: O15047 |
Catalog # | MBS841357 |
Price | $235 |
Order / More Info | Setd1a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |