YES1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityYES1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionNon-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and indu
Immunogenn/a
Other Names[Purified Mouse (Mab); Tyrosine-protein kinase Yes; 2.7.10.2; Proto-oncogene c-Yes; p61-Yes; YES1; YES]
Gene, Accession #[YES1], Gene ID: 7525, NCBI: NP_005424.1, UniProt: P07947
Catalog #MBS9216879
Price$165, $370
Order / More InfoYES1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSukegawa J.,et al.Mol. Cell. Biol. 7:41-47(1987). Nusbaum C.,et al.Nature 437:551-555(2005). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Sugawara K.,et al.Br. J. Cancer 63:508-513(1991). Krueger J.,et al.Oncogene 6:933-940(1991).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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