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Antigenic Specificity | PLCG1/Plc Gamma 1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. |
Immunogen | Immunogen: A synthesized peptide derived from human PLCG1. Subcellular Localization: Cell projection, lamellipodium. Cell projection, ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. |
Other Names | [1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1; PLC1], [PLCG1; PLCG1; PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1; PLC1; PLC-II; PLC-gamma-1] |
Gene, Accession # | [PLCG1], Gene ID: 5335, NCBI: NP_002651.2, UniProt: P19174 |
Catalog # | MBS179411 |
Price | $160, $340, $340 |
Order / More Info | PLCG1/Plc Gamma 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |