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Antigenic Specificity | Toll-like receptor 5 (TLR5) (CT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF- B, leading to the activation of TNF-alpha; and other cytokines (4). A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is |
Immunogen | Immunogen: Rabbit polyclonal TLR5 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR5. |
Other Names | [TLR5 (CT): Toll-like receptor 5], [TLR5; TLR5; TIL3; SLEB1; TIL3] |
Gene, Accession # | [TLR5], Gene ID: 7100, NCBI: NP_003259.2, UniProt: O60602 |
Catalog # | MBS395840 |
Price | $510 |
Order / More Info | Toll-like receptor 5 (TLR5) (CT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |