Superoxide Dismutase 1 (SOD1) Unfolded Beta Barrel Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySuperoxide Dismutase 1 (SOD1) Unfolded Beta Barrel
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoblot, Immunofluorescence (IF)
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DescriptionThis antibody recognizes a conformation-specific epitope where the beta barrel is unfolded. Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme that catalyzes the dismutation of the superoxide radical O2-to oxygen and hydrogen peroxide which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. SODs play an important role in antioxidant defense mechanisms. SOD1 contains Cu and Zn ions and exists as a homodimer in cell cytoplasm. Each SOD1 monomer folds into an eight-stranded Greek key beta-barrel. These strands are connected by seven external loops. Misfolding of SOD1 has been implicated in Amyotrophic Lateral Sclerosis (ALS).
ImmunogenImmunogen: Synthetic peptide corresponding to unfolded beta barrel (UbetaB) region at the N-terminus of SOD1.
Other Names[SOD1; Superoxide dismutase [Cu-Zn]; superoxide dismutase [Cu-Zn]; superoxide dismutase 1; Superoxide dismutase 1; hSod1], [SOD1; SOD1; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; hSod1]
Gene, Accession #[SOD1], Gene ID: 6647, NCBI: CAG46542, UniProt: P00441
Catalog #MBS191316
Price$405
Order / More InfoSuperoxide Dismutase 1 (SOD1) Unfolded Beta Barrel Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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