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Antigenic Specificity | GLE1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 656 of GLE1 |
Other Names | [nucleoporin GLE1 isoform 2; Nucleoporin GLE1; nucleoporin GLE1; GLE1 RNA export mediator; GLE1-like protein] |
Gene, Accession # | [GLE1], Gene ID: 2733, NCBI: NP_001490 |
Catalog # | MBS9405458 |
Price | $320 |
Order / More Info | GLE1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |