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Antigenic Specificity | JUP |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: JUP antibody detects endogenous levels of total JUP. Description: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.Function: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influ |
Immunogen | Immunogen: Purified recombinant fragment of human JUP expressed in E. Coli Subcellular Location: Cell Junction > Adherens Junction. Cell Junction > Desmosome. Cytoplasm > Cytoskeleton. Membrane. Cytoplasmic in a soluble and membrane-associated form. |
Other Names | [ARVD 12; ARVD12; Catenin (cadherin associated protein), gamma 80kDa; catenin (cadherin-associated protein) gamma (80kD); Catenin gamma; CTNNG; Desmoplakin 3; Desmoplakin III; Desmoplakin-3; Desmoplakin3; DesmoplakinIII; DP 3; DP III; DP3; DPIII; gamma catenin; Junction plakoglobin; JUP; OTTHUMP00000164732; OTTHUMP00000164735; OTTHUMP00000164738; PDGB; PKGB; PLAK_HUMAN; PLAKOGLOBIN] |
Gene, Accession # | [JUP], Gene ID: 3728, NCBI: NP_002221.1, UniProt: P14923 |
Catalog # | MBS9602747 |
Price | $235, $295, $370 |
Order / More Info | JUP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |