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Antigenic Specificity | Human CD49d (VLA-4) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CD49d/VLA-4. CD49d, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin beta4 chain. CD49d associates noncovalently with CD29, the integrin beta1 subunit, to form the beta4beta1 very late antigen-4 (VLA-4) heterodimer. Integrin beta4 can also associate with integrin beta7 to form the beta4beta7 heterodimer. It is expressed on most leukocytes, with the possible exception of neutrophils. VLA-4 mediates leukocyte binding to CD106/VCAM-1, and is involved in the migration of leukocytes from blood to tissue at sites of inflammation. VLA-4 can also provide a costimulatory signal to T cells for activation and proliferation. The beta4beta7 integrin heterodimer is expressed on a smal |
Immunogen | n/a |
Other Names | [CD49d-VLA-4] |
Gene, Accession # | [CD49d] |
Catalog # | MBS4152175 |
Price | $445 |
Order / More Info | Human CD49d (VLA-4) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |