GAD-65/67 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGAD-65/67
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
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DescriptionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gammaaminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulindependent diabetes. This gene may also play a role in the stiff man syndrome.Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.An important paralog of this gene is GAD2.GAD2 (Glutamate Decarboxylase 2) is a Protein Coding gene. Diseases associated with GAD2 include S
ImmunogenImmunogen: Synthesized peptide derived from the C-terminal region of human GAD-65/67. Observed MW: 65kDa
Other Names[GAD1, GAD, GAD67, Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD2, GAD65, Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65]
Gene, Accession #[GAD-65/67], UniProt: Q99259
Catalog #MBS2538061
Price$110, $150, $225
Order / More InfoGAD-65/67 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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