VISA Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | VISA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Paraffin*, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti VISA antibody recognizes the human Mitochondrial antiviral-signaling protein (MAVS), also known as Virus-induced-signalling-adaptor (VISA), and KIAA1271, VISA is a 540 amino acid outer mitochondrial membrane protein containing a single CARD domain. VISA is an important protein required for innate immune defence against viruses (Huang et al. 2014). VISA acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). VISA is believed to activate the same pathways following detection of extracellular dsRNA by TLR3 and it |
| Immunogen | Histology Positive Control Tissue: Mouse brain Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human VISA were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
| Other Names | [mitochondrial antiviral-signaling protein isoform 2; Mitochondrial antiviral-signaling protein; mitochondrial antiviral-signaling protein; CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; IFN-B promoter stimulator 1; interferon beta promoter stimulator protein 1; putative NF-kappa-B-activating protein 031N; virus-induced signaling adaptor; virus-induced-signaling adapter; mitochondrial antiviral signaling protein; CARD adapter inducing interferon beta; Cardif; Interferon beta promoter stimulator protein 1; IPS-1; Putative NF-kappa-B-activating protein 031N; Virus-induced-signaling adapter; VISA], [MAVS; MAVS; IPS1; VISA; IPS-1; CARDIF; IPS1; KIAA1271; VISA; MAVS; Cardif; IPS-1; VISA] |
| Gene, Accession # | [VISA], Gene ID: 57506, NCBI: NP_001193420.1, UniProt: Q7Z434 |
| Catalog # | MBS223807 |
| Price | $375 |
| Order / More Info | VISA Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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