PTK2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PTK2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PTK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Focal adhesion kinase (FAK) is a widely expressed cytoplasmic protein tyrosine kinase involved in integrin-mediated signal transduction. It plays an important role in the control of several biological processes, including cell spreading, migration, and survival (1). Activation of FAK by integrin clustering leads to autophosphorylation at Tyr397, which is a binding site for the Src family kinases PI3K and PLC gamma (2-5). Recruitment of Src family kinases results in the phosphorylation of Tyr407, Tyr576, and Tyr577 in the catalytic domain, and Tyr871 and Tyr925 in the carboxy-terminal region of FAK (6, 7). |
| Immunogen | Immunogen: A synthetic peptide of human PTK2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [FADK; FAK; FAK1; pp125FAK] |
| Gene, Accession # | [PTK2], Gene ID: 5747, NCBI: NP_001186578.1, UniProt: Q05397 |
| Catalog # | MBS8500986 |
| Price | $310 |
| Order / More Info | PTK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Parsons, J.T. et al. (2000) Oncogene 19, 5606-5613. 2. Schaller, M.D. et al. (1994) Mol. Cell. Biol. 14, 1680-1688. 3. Cobb, B.S. et al. (1994) Mol. Cell. Biol. 14, 147-155. 4. Chen, H.C. et al. (1996) J. Biol. Chem. 271, 26329-26334. 5. Zhang, X. et al. (1999) Proc. Natl. Acad. Sci. USA 96, 9021-9026. 6. Calalb, M.B. et al. (1995) Mol. Cell. Biol. 15, 954-963. 7. Schlaepfer, D.D. et al. (1994) Nature 372, 786-791. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies