Edit |   |
---|---|
Antigenic Specificity | CLN3 (Center), 235-263 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.48 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human CLN3. This gene encodes a protein that is involved in lysosomalfunction. Mutations in this, as well as other neuronalceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseasescommonly known as Batten disease or collectively known as neuronalceroid lipofuscinoses (NCLs). Many alternatively spliced transcriptvariants have been found for this gene. |
Immunogen | n/a |
Other Names | [Battenin; Batten disease protein; Protein CLN3; CLN3; BTS] |
Gene, Accession # | [CLN3], Gene ID: 1201, NCBI: NP_000077.1, UniProt: Q13286 |
Catalog # | MBS9204956 |
Price | $165, $370 |
Order / More Info | CLN3 (Center), 235-263 Antibody from MYBIOSOURCE INC. |
Product Specific References | Adams, H.R., et al. Dev Med Child Neurol 52(7):637-643(2010) Imielinski, M., et al. Nat. Genet. 41(12):1335-1340(2009) Sarpong, A., et al. Clin. Genet. 76(1):38-45(2009) Codlin, S., et al. J. Cell. Sci. 122 (PT 8), 1163-1173 (2009) : Tuxworth, R.I., et al. Hum. Mol. Genet. 18(4):667-678(2009) |