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Antigenic Specificity | HEPACAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HEPACAM antibody detects endogenous levels of HEPACAM. Function: Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.Subunit Structure: Homodimer. Dimer formation occurs predominantly through cis interactions on the cell surface. Part of a complex containing MLC1, TRPV4, AQP4 and ATP1B1.Post-translational Modifications: N-glycosylated.Similarity: The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. |
Immunogen | Immunogen: A synthesized peptide derived from human HEPACAM. Subcellular Location: Cytoplasm. Membrane. In MCF7 breast carcinoma and hepatic Hep3B and HepG2 cell lines, localization of HEPACAM is cell density-dependent. In well spread cells, localized to punctate structures in the perinuclear membrane, cytoplasm, and at cell surface of protusions. In confluent cells, localized predominantly to the cytoplasmic membrane, particularly in areas of cell-cell contacts. Colocalizes with CDH1. Tissue Sp |
Other Names | [FLJ25530; GlialCAM; HECAM_HUMAN; HEPACAM; Hepatocyte cell adhesion molecule; Protein hepaCAM] |
Gene, Accession # | [HEPACAM], Gene ID: 220296, NCBI: NP_689935.2, UniProt: Q14CZ8 |
Catalog # | MBS9603303 |
Price | $240, $280 |
Order / More Info | HEPACAM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |