Edit |   |
---|---|
Antigenic Specificity | KHDRBS3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 (PubMed:10564820, PubMed:19561594, PubMed:26758068). Involved in splice site selection of vascular endothelial growth factor (PubMed:15901763). In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved n |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 177-346 of human KHDRBS3 (NP 006549.1). |
Other Names | [Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile] |
Gene, Accession # | [KHDRBS3], Gene ID: 10656, NCBI: O75525.1, UniProt: O75525 |
Catalog # | MBS8546252 |
Price | $280 |
Order / More Info | KHDRBS3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |