B7 DC Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | B7 DC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human. |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for Programmed cell death 1 ligand 2 (PDCD1LG2) detection. Background: Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene. It is mapped to chromosome 9p24.2. PD-L2 is one of two ligands for programmed death-1 (PD-1), a member of the CD28 family of immuno-receptors. Northern blot analysis detect wide expression of PDL2, with highest levels in placenta, heart, pancreas, lung, and liver, and lower levels in spleen, lymph nodes, and thymus. PDL2 negatively regulates T cells and plays an essential role in immune tolerance. |
| Immunogen | Immunogen: E Coli-derived human B7 DC recombinant protein (Position: L20-T220). Human B7 DC shares 72.1% amino acid (aa) sequence identity with mouse B7 DC. |
| Other Names | [B7-DC; B7DC; B7 DC; Btdc; Butyrophilin B7 DC; Butyrophilin B7-DC; Butyrophilin B7DC; CD 273; CD273; CD273 antigen; PD L2; PD-L2; PD-1 ligand 2; PD1 ligand 2; PDCD 1 ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; PDL 2; PDL2; Q9BQ51; Programmed cell death 1 ligand 2], [PDCD1LG2; PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC] |
| Gene, Accession # | [PDCD1LG2], Gene ID: 80380, NCBI: NP_079515.2, UniProt: Q9BQ51 |
| Catalog # | MBS178510 |
| Price | $280 |
| Order / More Info | B7 DC Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: PDCD1LG2 programmed cell death 1 ligand 2.2. Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ (Mar 2001). PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2 (3): 261-8.3. Zhang, Y., Chung, Y., Bishop, C., Daugherty, B., Chute, H., Holst, P., Kurahara, C., Lott, F., Sun, N., Welcher, A. A., Dong, C.Regulation of T cell activation and tolerance by PDL2. Proc. Nat. Acad. Sci. 103: 11695-11700, 2006. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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